Grapefruits are a great food to add to your diet. If you have been asked to avoid grapefruit, it’s best to also avoid seville oranges (used to make orange marmalade), tangelos (a cross between tangerines and grapefruit), limes, and pomelos. Other Fruits That Have Similar Side Effectsįuranocoumarins, the compound in grapefruit that’s responsible for drug reactions, is also present in few other fruits belonging to the citrus family. If you have been asked to avoid grapefruit by your doctor, check the labels on fruit juice bottles and flavored drinks to ensure they don’t contain grapefruit.If you’re taking non-prescription drugs, read the Drug Facts label to find out if you are required to avoid grapefruit or other fruit juices.Read through your patient information sheet or medication guide to check if there is a mention of grapefruit in the list of foods to avoid when taking prescription drugs.In case you cannot, check for other juices that you need to avoid. Talk to your doctor about having fresh grapefruit or grapefruit juice when you’re on medication.Safety Tips To Avoid Side Effects Of Grapefruit 17 So if you have a history of citrus allergy, it’s recommended that you avoid grapefruit along with other fruits from the citrus family. Allergic reactions to profilin are intensified when exposed to airborne allergens like grass pollen.
16 Studies have also shown that there is a connection between allergens in food and those in the air. Citrus allergy has been reported to orange, mandarin, and grapefruit, but contrary to the name of the allergy, it’s not caused by citric acid.Ĭitrus allergy is caused by immune responses to lipid transfer proteins known as profilin and pectin. In severe cases, an allergic reaction could cause anaphylaxis, a potentially life‑threatening reaction that requires immediate medical attention. If you are allergic to a particular citrus fruit, it’s highly likely that others too can trigger an allergic reaction. Grapefruit belongs to the family of citrus fruits which also include limes, lemons, and oranges. If you’re taking drugs that fall under any of the above categories, talk to your doctor about alternatives. Also, you might not have to give up grapefruit just yet as it does not react with all the drugs in a given category. Since grapefruit interferes with the metabolic process of drug absorption, its side effects are usually limited to drugs taken orally. While grapefruit makes other drugs more potent, in the case of fexofenadine, it decreases the absorption making the drug less effective.
Just a single glass of grapefruit juice has been found to increase the concentration of this drug. Amiodarone: This drug is an antiarrhythmic medication used to treat and prevent several of types of irregular heartbeats.Having grapefruit juice considerably increases buspirone concentrations. Buspirone: It is used to treat symptoms of anxiety, such as fear, tension, irritability, and dizziness.
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